Study tracker · Healing · Gut
BPC-157
Updated 19 Oct 2026 · Peptilex evidence grade D (A = approved, large trials · D = mainly animal studies)
More than 100 animal studies report faster healing of tendons, ligaments, muscle, bone and the gut lining. The first systematic review of all human studies (2026: 3 small studies, 30 people) found symptom improvement in most participants and no treatment-related side effects, and a randomized trial after rotator cuff surgery (University of Arkansas) is scheduled to start in 2027.
226PubMed papers
56Human studies
0Randomized trials
2Registered studies
1Ongoing / starting
0Phase 3+
Registered trials
From ClinicalTrials.gov, matched by name in the study title.
| Study | Phase | Status | Participants | Start |
|---|---|---|---|---|
| Impact of BPC-157 on Recovery Following Rotator Cuff Repair Surgery NCT07803250 · University of Arkansas | Phase 1 | Starting soon | 30 | 2027-01 |
| PCO-02 - Safety and Pharmacokinetics Trial NCT02637284 · PharmaCotherapia d.o.o. | Phase 1 | Status unknown | 42 | 2015-10 |
1 further registry entry from a sponsor we could not verify is not listed.
Selected publications
From PubMed. The full story – mechanism, all results, risks – is in the BPC-157 profile of the book.
- 2026Human evidence for BPC-157 in orthopaedic and regenerative medicine: a systematic review of efficacy and safetyPoolton JT et al. · Acta orthopaedica Belgica · PMID 42885452
- 2026Case Report: Regenerative peptides for Inferior alveolar nerve injury: a narrative review with hypothesis-generating three clinical casesFroum S et al. · Frontiers in oral health · PMID 42876687
- 2026Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine PhysiciansMayfield CK et al. · The American journal of sports medicine · PMID 41476424
- 2026Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future DirectionsRahman OF et al. · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · PMID 41490200
- 2026Protective effects of BPC 157 in rats with experimentally induced lower extremity ischemia-reperfusion injuryYıldırım AK et al. · Scientific reports · PMID 42204242
- 2025Injectable Therapeutic Peptides-An Adjunct to Regenerative Medicine and Sports Performance?DeFoor MT et al. · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association · PMID 39265666
- 2022Cytoprotective gastric pentadecapeptide BPC 157 resolves major vessel occlusion disturbances, ischemia-reperfusion injury following Pringle maneuver, and Budd-Chiari syndromeSikiric P et al. · World journal of gastroenterology · PMID 35125818
- 2021Intra-Articular Injection of BPC 157 for Multiple Types of Knee PainLee E et al. · Alternative therapies in health and medicine · PMID 34324435
