Efficacy and Safety of GLP-1 Receptor Agonists, Dual Agonists, and Retatrutide for Weight Loss in Adults With Overweight or Obesity: A Bayesian NMA
Obesity · 2025
Research news
9 new papers and 1 registered trials added to our tracker since the previous update.
Obesity · 2025
Endocrinology, Diabetes & Metabolism · 2025
JAMA · 2026
Source: PubMed and ClinicalTrials.gov via the Peptilex study database
Meta-analysisWen J et al. · Endocrinology, Diabetes & MetabolismPMID 40184508
Tirzepatide in Adults With Type 1 Diabetes: A Phase 2 Randomized Placebo-Controlled Clinical Trial
Human RCTPhase 2Snaith JR et al. · Diabetes CarePMID 41264593
Human RCTPhase 1Martin CK et al. · Nature MedicinePMID 40555748
Tirzepatide did not impact metabolic adaptation in people with obesity, but increased fat oxidation
Human RCTPhase 1Ravussin E et al. · Cell MetabolismPMID 40203836
Meta-analysisSinha B et al. · ObesityPMID 40685589
Human RCTPhase 3Bellido V et al. · The LancetPMID 42810372
Teriparatide Plus Zoledronic Acid for Osteogenesis Imperfecta: A Randomized Clinical Trial
Human RCTHald JD et al. · JAMAPMID 42133304
Human RCTRamchand SK et al. · Journal of Bone and Mineral ResearchPMID 41128757
Animal studyDemirtaş H et al. · MedicinaPMID 40005408
| Study | Phase | Status | Participants | Start |
|---|---|---|---|---|
| Thymalfasin for Immune Recovery in Adults With Sepsis NCT07866118Shanghai Zhongshan Hospital | – | Recruiting | 60 | Oct 2026 |
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