Peptide research update · 19 Oct 2026

MOTS-cD

1. 2026

   MOTS-c attenuates hyperoxia-induced neonatal cardiac injury by inhibiting oxeiptosis via maintaining the KEAP1-PGAM5 interaction

   Animal studyLi SH et al. · Life SciencesPMID 42128272

2. 2026

   MOTS-c primes adrenal cortex metabolism without directly driving steroidogenesis

   Animal studyBlatkiewicz M et al. · Folia Histochemica Et CytobiologicaPMID 41811086

3. 2026

   MOTS-c Protects Against Acetaminophen-induced Liver Injury through the MAPK Signaling Pathway

   Animal studyLi N et al. · Protein and Peptide LettersPMID 41764620

4. 2025

   MOTS-c mimics exercise to combat diabetic liver fibrosis by targeting Keap1-Nrf2-Smad2/3

   Animal studyChen F et al. · Scientific ReportsPMID 40425777

EpitalonD

1. 2025

   Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity

   Lab studyAl-Dulaimi S et al. · BiogerontologyPMID 40908429

2. 2025

   The Antioxidant Tetrapeptide Epitalon Enhances Delayed Wound Healing in an in Vitro Model of Diabetic Retinopathy

   Lab studyGatta M et al. · Stem Cell Reviews and ReportsPMID 40493162

3. 2025

   Epitalon-activated telomerase enhance bovine oocyte maturation rate and post-thawed embryo development

   Lab studyUllah S et al. · Life SciencesPMID 39788414

TirzepatideA

1. 2025

   Tirzepatide for adults living with obesity

   Meta-analysisFranco JV et al. · Cochrane Database of Systematic ReviewsPMID 41161687

2. 2025

   Gastrointestinal safety of semaglutide and tirzepatide vs. placebo in obese individuals without diabetes: a systematic review and meta analysis

   Meta-analysisSafwan M et al. · Annals of Saudi MedicinePMID 40189856

3. 2026

   Tirzepatide Versus Intensified Conventional Care After 2 Years of Treatment in Early Type 2 Diabetes : A Randomized Clinical Trial

   Human RCTDel Prato S et al. · Annals of Internal MedicinePMID 42184419

BPC-157D

1. 2026

   Human evidence for BPC-157 in orthopaedic and regenerative medicine: a systematic review of efficacy and safety

   Systematic reviewPoolton JT et al. · Acta Orthopaedica BelgicaPMID 42885452

2. 2026

   Protective effects of BPC 157 in rats with experimentally induced lower extremity ischemia-reperfusion injury

   Animal studyYıldırım AK et al. · Scientific ReportsPMID 42204242

RetatrutideB

1. 2025

   Efficacy and safety of triple hormone receptor agonist retatrutide for the management of obesity: a systematic review and meta-analysis

   Meta-analysisTewari J et al. · Expert Review of Clinical PharmacologyPMID 39817343

2. 2026

   Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes

   Human RCTPhase 2Pearson MJ et al. · J Clin Endocrinol MetabPMID 42135195

SemaglutideA

SemaxC

1. 2025

   The Effect of Peptide Semax, an ACTH(4-10) Analogue, on Intracellular Calcium Dynamics in Rat Brain Neurons

   Animal studyKolbaev SN et al. · Bulletin of Experimental Biology and MedicinePMID 41171324

Teriparatide & abaloparatideA

1. 2025

   Perioperative teriparatide for preventing proximal junctional kyphosis and failure in patients with osteoporosis after adult thoracolumbar spinal deformity surgery: a prospective randomized controlled trial

   Human RCTPark JH et al. · Osteoporosis InternationalPMID 40100350