Peptilex – The Peptide Encyclopedia
- 34 peptides – from semaglutide to BPC-157 – in one book
- An evidence grade (A–E) and the key studies for every peptide
- Where each one stands in 2026 – US, EU and Switzerland
Skin & beauty
Palmitoyl pentapeptide-4 (Matrixyl)
- Type
- Signal peptide: five amino acids with an attached fatty-acid chain
- Main use or focus
- Fine lines and wrinkles (topical)
- Also known as
- Matrixyl
Key studies from the book
Double-blind split-face trial, 93 women, 12 weeks; fine lines and wrinkles improved more than with the placebo cream.
Robinson LR et al. – International Journal of Cosmetic Science, 2005Review of signal peptides and other cosmeceutical peptides.
Schagen SK – Cosmetics, 2017
All key studies, risks and open questions are in the book.
Research at a glance
All papers20
Human studies10
Animal studies only1
Randomized trials1
Meta-analyses & systematic reviews0
Source: PubMed and ClinicalTrials.gov via the Peptilex study database
Go deeper
Full profile in the book
What it is, how it acts, the key studies, risks and open questions.
Registered trials
ClinicalTrials.gov · name in study title · ongoing first
No registered trial yet on ClinicalTrials.gov.
Latest key papers
PubMed · newest first
- 2004
Human RCTRöper B et al. · Strahlentherapie Und OnkologiePMID 15127162