Peptilex
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The book

Hormones & growth

Sermorelin

Peptilex evidence grade ABCDEUpdated 19 Oct 2026 How grades work
Type
GHRH analogue (first 29 amino acids of natural GHRH)
Main use or focus
Formerly: diagnosis and treatment of growth hormone deficiency in children. Today promoted for "anti-aging"

Key studies from the book

  • 110 children with growth hormone deficiency; growth rate rose from 4.1 to 8.0 centimeters per year within six months.

    Thorner M et al. – Journal of Clinical Endocrinology & Metabolism, 1996
  • Randomized, 19 older adults, 16 weeks; IGF-1 and skin thickness up, lean mass up in men.

    Khorram O et al. – Journal of Clinical Endocrinology & Metabolism, 1997
  • 11 healthy older men, 6 weeks; growth hormone up, two of six strength measures improved.

    Vittone J et al. – Metabolism, 1997

All key studies, risks and open questions are in the book.

Research at a glance

Publications by typePubMed, all years
All papers25
Human studies18
Animal studies only0
Randomized trials0
Meta-analyses & systematic reviews0

Source: PubMed and ClinicalTrials.gov via the Peptilex study database

Go deeper

Full profile in the book

What it is, how it acts, the key studies, risks and open questions.

Peptilex – The Peptide Encyclopedia, book cover

Peptilex – The Peptide Encyclopedia

  • 34 peptides – from semaglutide to BPC-157 – in one book
  • An evidence grade (A–E) and the key studies for every peptide
  • Where each one stands in 2026 – US, EU and Switzerland

Formats: Kindle · Paperback · Hardcover

Amazon store: amazon.com · Change store

Registered trials

ClinicalTrials.gov · name in study title · ongoing first

No registered trial yet on ClinicalTrials.gov.

Latest key papers

PubMed · newest first

  1. 2006

    Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?

    ReviewWalker RF et al. · Clinical Interventions in AgingPMID 18046908

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